What are Nic Salt eJuices? You've heard of them, but should you use them? Nicotine salts are causing smokers and vapers to quit cigarettes for good. Nicotine salts allow you to vape at higher nicotine concentrations without the intrusive throat hit you'd expect. While these are very effective, you should know that they should not be used with your normal sub-ohm device. Nic Salt E-Liquid should be used with low powered (high ohm) devices only.